Nearly a year ago, Spider-Man hurled the dangerous madman called Zodiac a full year into the future. That means Zodiacs had a whole year to prepare for their rematch! And when the web-slinger pays Doctor Stranges Sanctum Sanctorum a visit looking for a consult, he finds theres a new Sorcerer Supreme in town: Loki! And this newest Master of the Mystic Arts has his own unique brand of magic! Meanwhile, Norman Osborn has scoured the globe for a cure to the genetic tampering that prevents him from becoming the Green Goblin and at long last, hes about to find it! Plus: Betty Brant searches for answers when she receives a voicemail from...her late husband, Ned Leeds! All this and the uncanny threat of Clash! Collecting AMAZING SPIDER-MAN (2015) #25 (B STORY), #794-796 and ANNUAL #42. Rated T